Metabolic Syndrome Pathophysiology and Pharmacology 03:14

Risk Factors for Metabolic Syndrome include Age, Obesity, Physical Inactivity, Insulin Resistance, Oxidative Stress, and Chronic Inflammation. 

Pharmacological interventions focus on controlling cardiovascular disease risk including blood pressure and cholesterol​​​​​.

Effects on exercise include alterations in HR and blood pressure responses (blunted HR response) lowered BP during exercise- so must be careful of increasing exercise intensity too much and must watch for hypotension following exercise. In addition, some medications such as fibrates can increase the risk of rhabdomyolysis, so exercise intensity should be monitored and not progressed too rapidly.